Exercise and Neuroprotection in Human Parkinson’s: The Long and Winding Road

"It is exercise alone that supports the spirits, and keeps the mind in vigor." Marcus Tullius Cicero "Lack of activity destroys the good condition of every human being." Plato Introduction: I have been convinced for a while that exercise is medicine. This blog post summarizes two publications: Crotty, Grace F., and Michael A. Schwarzschild. "Chasing …

The Aging Immune System and Parkinson’s

"Come grow old with me. The best is yet to be." William Wordsworth "As long as I am breathing, in my eyes, I am just beginning." Criss Jami Introduction: Recently, an exciting and in-depth review article about inflammation and the immune system and their dysfunction in the pathway of Parkinson's was published. The citation for …

Role of Palmitoylethanolamide to Control Neuroinflammation and Potential Therapy for Parkinson’s

"Our destiny is not determined by the number of times we stumble but by the number of times we rise up, dust ourselves off, and move forward." Dieter F. Uchtdorf "My motto was always to keep swinging. Whether I was in a slump or feeling bad or having trouble off the field, the only thing …

Golf and Reducing the Risk of Falls in Parkinson’s

"The harder you work, the luckier you get." Gary Player "The only thing a golfer needs is more daylight." Ben Hogan Précis: The sport of golf provides a low-impact all-around form of exercise that improves balance and flexibility and promotes a range of motion by activation of muscles in the upper and lower body. If you …

Brief Report: Low-Dose Niacin Improves Motor Function in Parkinson’s

"If you can't explain it simply, you don't understand it well enough." Albert Einstein "Be a voice not an echo." Albert Einstein Abstract: The VA Medical Center in Augusta, Georgia, reported the results of a six-month single-center, double-blind, placebo-controlled randomized study using Parkinson's patients with early- and late-stage disease. They asked the question of whether …

Science Sunday: Ashwagandha and Parkinson’s

"Live neither in the past nor in the future, but let each day absorb all your interest, energy and enthusiasm. The best preparation for tomorrow is to live today superbly well." William Osler "It is more important to know what sort of person has a disease than to know what sort of disease a person …

Potential Anti-Aging and Neuroprotection Strategy for Parkinson’s

"The years teach much which the days never know." Ralph Waldo Emerson "Old age is not a disease - it is strength and survivorship, triumph over all kinds of vicissitudes and disappointments, trials and illnesses." Maggie Kuhn Introduction: This blog post presents a strategy to possibly reduce aging and it may also be neuroprotective in …

Botulinum Toxin for Treatment of Dystonia, Sialorrhea (Drooling), and Tremor in Parkinson’s

"Being happy doesn't mean that everything is perfect. It means that you've decided to look beyond the imperfections." Gerard Way "Rules for Happiness: something to do, someone to love, something to hope for." Immanuel Kant Introduction:  I have a new friend with Parkinson's. He has always been very active and genuinely enjoys playing golf. However, he …

Journey With Parkinson’s: (Part 2) A Different Side of Life

"Yesterday is but today's memory, and tomorrow is today's dream." Khalil Gibran "Time is free, but it's priceless. You can't own it, but you can use it. You can't keep it, but you can spend it. Once you've lost it you can never get it back." Harvey Mackay Introduction: I am a scientist, trained as …

Basal Ganglia, Nigrostriatal Pathway and Parkinson’s

"Hope arouses, as nothing else can arouse, a passion for the possible." William Sloane Coffin "Walk on, walk on with hope in your heart, and you'll never walk alone, you'll never walk alone." Oscar Hammerstein II Introduction: I have been trying to learn more about brain physiology and the inner workings as it relates to …

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