Potential Anti-Aging and Neuroprotection Strategy for Parkinson’s

"The years teach much which the days never know." Ralph Waldo Emerson "Old age is not a disease - it is strength and survivorship, triumph over all kinds of vicissitudes and disappointments, trials and illnesses." Maggie Kuhn Introduction: This blog post presents a strategy to possibly reduce aging and it may also be neuroprotective in …

Botulinum Toxin for Treatment of Dystonia, Sialorrhea (Drooling), and Tremor in Parkinson’s

"Being happy doesn't mean that everything is perfect. It means that you've decided to look beyond the imperfections." Gerard Way "Rules for Happiness: something to do, someone to love, something to hope for." Immanuel Kant Introduction:  I have a new friend with Parkinson's. He has always been very active and genuinely enjoys playing golf. However, he …

Journey With Parkinson’s: (Part 2) A Different Side of Life

"Yesterday is but today's memory, and tomorrow is today's dream." Khalil Gibran "Time is free, but it's priceless. You can't own it, but you can use it. You can't keep it, but you can spend it. Once you've lost it you can never get it back." Harvey Mackay Introduction: I am a scientist, trained as …

Basal Ganglia, Nigrostriatal Pathway and Parkinson’s

"Hope arouses, as nothing else can arouse, a passion for the possible." William Sloane Coffin "Walk on, walk on with hope in your heart, and you'll never walk alone, you'll never walk alone." Oscar Hammerstein II Introduction: I have been trying to learn more about brain physiology and the inner workings as it relates to …

Importance of Magnesium in the Brain and Magnesium Threonate is Neuroprotective in a Mouse Model of Parkinson’s

"The world may be broken, but hope is not crazy." John Green "Our eternal message of hope is that dawn will come." Martin Luther King, Jr. Introduction:  Epidemiological studies show that magnesium deficiency is associated with a Parkinson's like syndrome called Parkinson-Dementia Syndrome (PDC). PDC patients have progressive cognitive decline, parkinsonian, and the loss of the …

The 2019 World Parkinson Congress in Kyoto, Japan

"Learning is not attained by chance, it must be sought for with ardor and diligence." Abigail Adams "Believe in yourself and all that you are. Know that there is something inside you that is greater than any obstacle." Christian D. Larson Introduction to the 5th World Parkinson Congress (WPC) in Kyoto, Japan from June 4-7, …

Manganese-induced Parkinsonism Compared to Parkinson’s Disease

"Science is a way of thinking much more than it is a body of knowledge." Carl Sagan "Imagination is more important than knowledge." Albert Einstein What is Manganese? Manganese is abbreviated by the symbol Mn and it is atomic number 25 (see Periodic Table of the Elements).  Manganese is considered a transition metal, which is …

Human Gut Microbes Identified That Process Levodopa

"Symbiosis is a much higher reflection of intelligent life." Frederick Lenz "Why do we do basic research? To learn about ourselves." Walter Gilbert Overview: Reading the article entitled "Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism" from V. Maini Rekdal et al., Science 364, eaau6323 (2019) (DOI: 10.1126/science.aau6323- open access) made …

Neurological Mayhem by Dual Antioxidative and Anti-inflammatory Agents in Aged Parkinson’s Mice

"No person was ever honored for what he received. Honor has been the reward for what he gave." Calvin Coolidge "The most reliable way to predict the future is to create it." Abraham Lincoln Introduction: Recently, Jeff Keegan asked me if I had seen the paper by Gil-Martínez et al., an established Parkinson's research group …

Whey Protein Supplements May Increase Glutathione in Parkinson’s

"Basic research is what I am doing when I don't know what I am doing." Wernher von Braun "As far as the laws of mathematics refer to reality, they are not certain, and as far as they are certain, they do not refer to reality." Albert Einstein Overview: In 1989, Riederer and others demonstrated that …