Wellness Checklist for Life in the Presence of Parkinson’s

"Today is the first day of the rest of your life." Abbie Hoffman "Your life is a work of art that you will work on the rest of your life." Richard Blanco Introduction: The year is closing in on us, one for the record books; a year like no other, it would seem. The Pandemic …

Treating Parkinson’s with Carbidopa/Levodopa

"If you are always trying to be normal you will never know how amazing you can be." Maya Angelou "Hope and fear cannot occupy the same space. Invite one to stay." Maya Angelou Précis: This blog post's primary goal is to present an overview of Carbidopa/Levodopa (originally named Sinemet) for treating Parkinson's. A secondary objective was …

Basal Ganglia, Nigrostriatal Pathway and Parkinson’s

"Hope arouses, as nothing else can arouse, a passion for the possible." William Sloane Coffin "Walk on, walk on with hope in your heart, and you'll never walk alone, you'll never walk alone." Oscar Hammerstein II Introduction: I have been trying to learn more about brain physiology and the inner workings as it relates to …

A Parkinson’s Diagnosis: You Still Control Your Life

"Your life is a work of art that you will work on the rest of your life." Richard Blanco "Today is the first day of the rest of your life, and if you screw that up, you can start again tomorrow." Ingrid Weir A Not So Typical "Anniversary" Blog Post:Six years ago this week, I …

The Practical Matter of Carrying Medication for Treating Parkinson’s

"Trust yourself. Create the kind of self that you will be happy to live with all your life." Golda Meir "Start where you are, use what you have." Arthur Ashe Introduction: Within 24 hours of arriving in Kyoto, Japan for the World Parkinson Congress (June 2019), I was asked by several people, "How did I …

The Uncertainty of Parkinson’s

"In these matters the only certainty is that nothing is certain." Pliny the Elder "Knowledge is an unending adventure at the edge of uncertainty." Jacob Bronowski Précis: There are many motor and non-symptoms in Parkinson's, which gives us our own individual expression pattern of this chronic neurodegenerative disease. A common thread we share is linked …

Brief Report: Hair Loss Linked to Dopamine Agonists

"It is foolish to pluck out one's hair for sorrow, as if grief could be assuaged by baldness." Marcus Tullius Cicero "Anyone can be confident with a full head of hair. But a confident bald man - there's your diamond in the rough." Larry David Introduction: When you play golf, they frequently pair you up …

Human Gut Microbes Identified That Process Levodopa

"Symbiosis is a much higher reflection of intelligent life." Frederick Lenz "Why do we do basic research? To learn about ourselves." Walter Gilbert Overview: Reading the article entitled "Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism" from V. Maini Rekdal et al., Science 364, eaau6323 (2019) (DOI: 10.1126/science.aau6323- open access) made …

Journey with Parkinson’s: Brief Reports on Current Research/Issues

"There is a single light of science, and to brighten it anywhere is to brighten it everywhere." Isaac Asimov “Live neither in the past nor in the future, but let each day’s work absorb your entire energies, and satisfy your widest ambition.”  Sir William Osler Introduction: For the following reasons, I would like to introduce and …

Dopamine Agonists and Impulse Control Disorders in Parkinson’s

"Whenever you are immersed in compulsive thinking, you are avoiding what is. You don't want to be where you are. Here, Now." Eckhart Tolle "Somewhere between obsession and compulsion is impulse." Alexander Pushkin Introduction: In the latest issue of Neurology (June, 2018), Dr. Corvol and collaborators in Paris, France, present the results of a long-term …