The Practical Matter of Carrying Medication for Treating Parkinson’s

"Trust yourself. Create the kind of self that you will be happy to live with all your life." Golda Meir "Start where you are, use what you have." Arthur Ashe Introduction: Within 24 hours of arriving in Kyoto, Japan for the World Parkinson Congress (June 2019), I was asked by several people, "How did I …

The Uncertainty of Parkinson’s

"In these matters the only certainty is that nothing is certain." Pliny the Elder "Knowledge is an unending adventure at the edge of uncertainty." Jacob Bronowski Précis: There are many motor and non-symptoms in Parkinson's, which gives us our own individual expression pattern of this chronic neurodegenerative disease. A common thread we share is linked …

Brief Report: Hair Loss Linked to Dopamine Agonists

"It is foolish to pluck out one's hair for sorrow, as if grief could be assuaged by baldness." Marcus Tullius Cicero "Anyone can be confident with a full head of hair. But a confident bald man - there's your diamond in the rough." Larry David Introduction: When you play golf, they frequently pair you up …

Human Gut Microbes Identified That Process Levodopa

"Symbiosis is a much higher reflection of intelligent life." Frederick Lenz "Why do we do basic research? To learn about ourselves." Walter Gilbert Overview: Reading the article entitled "Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism" from V. Maini Rekdal et al., Science 364, eaau6323 (2019) (DOI: 10.1126/science.aau6323- open access) made …

Journey with Parkinson’s: Brief Reports on Current Research/Issues

"There is a single light of science, and to brighten it anywhere is to brighten it everywhere." Isaac Asimov “Live neither in the past nor in the future, but let each day’s work absorb your entire energies, and satisfy your widest ambition.”  Sir William Osler Introduction: For the following reasons, I would like to introduce and …

Dopamine Agonists and Impulse Control Disorders in Parkinson’s

"Whenever you are immersed in compulsive thinking, you are avoiding what is. You don't want to be where you are. Here, Now." Eckhart Tolle "Somewhere between obsession and compulsion is impulse." Alexander Pushkin Introduction: In the latest issue of Neurology (June, 2018), Dr. Corvol and collaborators in Paris, France, present the results of a long-term …

Dopamine Agonist Withdrawal Syndrome (DAWS) in Parkinson’s

"Some remedies are worse than the disease." Publilius Syrus "Each patient carries his own doctor inside him." Norman Cousins Summary: Dopamine agonists are widely used in the treatment of Parkinson's, especially as a first-line therapy. Some patients on a dopamine agonist experience side-effects that require either tapering or discontinuation of the drug.  First described in …