COMT Inhibitors in Parkinson’s: Tell Me More, Tell Me More

"If the brain were so simple we could understand it, we would be so simple we couldn't." Lyall Watson "The human brain doesn't come with an instruction manual." Bill Engvall Précis: This blog post aims to present an overview of COMT inhibitors in Parkinson's. A second goal of this blog post is a brief review …

2023 Parkinson’s Awareness Month and 120 Quotes to Support Your Journey

"He who has health, has hope; and he who has hope, has everything." Thomas Carlyle "Health is like money, we never have a true idea of its value until we lose it." Josh Billings Introduction: For whatever reason, quotes have been a part of most of my blog posts. It is not like I have …

World Parkinson’s Disease Day (11 April 2023)

"Hardships often prepare ordinary people for an extraordinary destiny." C.S. Lewis "Nothing in life is to be feared; it is only to be understood. Now is the time to understand more so that we may fear less." Marie Curie The Naming of the Disease: Dr. Jean-Martin Charcot, considered a pioneering clinician of modern neurology, suggested …

Parkinson’s Awareness Month 2023: Information, Advice, and Recap of the Journey From 2015-Present

“Look to the nervous system as the key to maximum health.” Galen “If we could give every individual the right amount of nourishment and exercise, not too little and not too much, we would have found the safest way to health.” Hippocrates Introduction: This blog post has five goals- #1, Introduce Parkinson's Awareness Month: (i) Describe the …

Parkinson’s and the Lesson Learned on the Bermuda Railway Trail Walk

"It does not matter how slowly you go as long as you do not stop." Confucius "You just can't beat the person who never gives up." Babe Ruth Preface to the Story: One of our favorite vacation places is Bermuda. The small 20-something square mile island, the water, the scenes, the amicable people (~60,000 inhabitants), and …

Finding Your Ikigai in the Presence of Parkinson’s

"My mission in life is not merely to survive, but to thrive; and to do so with some passion, some compassion, some humor, and some style" Maya Angelou "Resilience is all about being able to overcome the unexpected. Sustainability is about survival. The goal of resilience is to thrive." Jamais Cascio Introduction: The COVID-19 pandemic …

Parkinson’s and Axial Rotation (Part 3, Lumbar Spine)

"Tentative efforts lead to tentative outcome." Epictetus "Patients should have rest, food, fresh air, and exercise - the quadrangle of health." William Osler Background: The function of our spine, all the bones and muscles, and associated tissues connected to this region are crucial for everyday life. A prevalent injury or pain that many people typically have …

Immunomodulating Activity of an Extract from Ashwagandha: Implications for Treatment of Parkinson’s

"The mind, in addition to medicine, has powers to turn the immune system around." Jonas Salk "As you begin to heal the inner you, you alter your immune system." Wayne Dyer Introduction: The current blog post is focused on reviewing an immunomodulating action of an extract from Ashwagandha. Furthermore, I will comment on the use …

Brief Report: Pallidothalamic Tractotomy by Focused Ultrasound for Parkinson’s Disease

"Patience and fortitude conquer all things." Ralph Waldo Emerson "I know of no higher fortitude than stubborness in the face of overwhelming odds." Louis Nizer Overview: Recently, I reviewed a clinical trial involving ablation of the globus pallidus by focused ultrasound to treat Parkinson's (click here to read this blog post). Some time ago, I …

Focused Ultrasound Ablation Therapy of the Globus Pallidus for Parkinson’s

"Be brave. Take risks. Nothing can substitute experience." Paulo Coelho "Resilience is not what happens to you. It’s how you react to, respond to, and recover from what happens to you." Jeffrey Gitomer Introduction: The clinical trial results were published in the New England Journal of Medicine by Krishna et al. (2023), dealing with ultrasound treatment …