Effect of Posture and Motility on Drug Availability in the Human Stomach

"The good thing about science is that it's true whether or not you believe in it." Neil deGrasse Tyson "Imagination is more important than knowledge." Albert Einstein Introduction:  Taking something by mouth is a common and relatively easy way to administer a drug. By contrast, when you carefully consider the route, it is a more complex …

The Aging Immune System and Parkinson’s

"Come grow old with me. The best is yet to be." William Wordsworth "As long as I am breathing, in my eyes, I am just beginning." Criss Jami Introduction: Recently, an exciting and in-depth review article about inflammation and the immune system and their dysfunction in the pathway of Parkinson's was published. The citation for …

Science Sunday: Cinnamon’s Neuroprotective Potential in Parkinson’s

"The doctor of the future will no longer treat the human frame with drugs, but rather will cure and prevent disease with nutrition." Thomas A. Edison "Our food should be our medicine and our medicine should be our food." Hippocrates Introduction: Besides being used in foods as a spice, cinnamon has been used for many …

Role of Palmitoylethanolamide to Control Neuroinflammation and Potential Therapy for Parkinson’s

"Our destiny is not determined by the number of times we stumble but by the number of times we rise up, dust ourselves off, and move forward." Dieter F. Uchtdorf "My motto was always to keep swinging. Whether I was in a slump or feeling bad or having trouble off the field, the only thing …

Addendum: Low-Dose Niacin Improves Motor Function in Parkinson’s

"Information is not knowledge. The only source of knowledge is experience. You need experience to gain wisdom." Albert Einstein "Don't listen to the person who has the answers; listen to the person who has the questions." Albert Einstein Addendum: In the blog reviewing niacin as a treatment strategy for improving motor function in Parkinson's (click here to …

Brief Report: Low-Dose Niacin Improves Motor Function in Parkinson’s

"If you can't explain it simply, you don't understand it well enough." Albert Einstein "Be a voice not an echo." Albert Einstein Abstract: The VA Medical Center in Augusta, Georgia, reported the results of a six-month single-center, double-blind, placebo-controlled randomized study using Parkinson's patients with early- and late-stage disease. They asked the question of whether …

Science Sunday: Ashwagandha and Parkinson’s

"Live neither in the past nor in the future, but let each day absorb all your interest, energy and enthusiasm. The best preparation for tomorrow is to live today superbly well." William Osler "It is more important to know what sort of person has a disease than to know what sort of disease a person …

Science Tuesday: Sublingual Carbidopa/Levodopa

"The human brain doesn't come with an instruction manual." Bill Engvall "The great events of the world take place in the brain." Oscar Wilde Levodopa: Levodopa markedly improves motor symptoms for the majority of people with Parkinson’s. The pharmacological effectiveness of levodopa is quite good; however, it has less efficiency in controlling the non-motor symptoms. …

Potential Anti-Aging and Neuroprotection Strategy for Parkinson’s

"The years teach much which the days never know." Ralph Waldo Emerson "Old age is not a disease - it is strength and survivorship, triumph over all kinds of vicissitudes and disappointments, trials and illnesses." Maggie Kuhn Introduction: This blog post presents a strategy to possibly reduce aging and it may also be neuroprotective in …

Treating Parkinson’s with a Dopamine Agonist: The Ropinirole Taper

"The key to change is to let go of fear." Rosanne Cash "Worry does not empty tomorrow of its sorrow. It empties today of its strength." Corrie Ten Boom Introduction: Seven years ago, when diagnosed with Parkinson's, I began taking Ropinirole, a dopamine agonist. And in the last month, I decided to stop taking Ropinirole …

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