Science Tuesday: Sublingual Carbidopa/Levodopa

"The human brain doesn't come with an instruction manual." Bill Engvall "The great events of the world take place in the brain." Oscar Wilde Levodopa: Levodopa markedly improves motor symptoms for the majority of people with Parkinson’s. The pharmacological effectiveness of levodopa is quite good; however, it has less efficiency in controlling the non-motor symptoms. …

Potential Anti-Aging and Neuroprotection Strategy for Parkinson’s

"The years teach much which the days never know." Ralph Waldo Emerson "Old age is not a disease - it is strength and survivorship, triumph over all kinds of vicissitudes and disappointments, trials and illnesses." Maggie Kuhn Introduction: This blog post presents a strategy to possibly reduce aging and it may also be neuroprotective in …

Treating Parkinson’s with a Dopamine Agonist: The Ropinirole Taper

"The key to change is to let go of fear." Rosanne Cash "Worry does not empty tomorrow of its sorrow. It empties today of its strength." Corrie Ten Boom Introduction: Seven years ago, when diagnosed with Parkinson's, I began taking Ropinirole, a dopamine agonist. And in the last month, I decided to stop taking Ropinirole …

A Parkinson’s Diagnosis: You Still Control Your Life

"Your life is a work of art that you will work on the rest of your life." Richard Blanco "Today is the first day of the rest of your life, and if you screw that up, you can start again tomorrow." Ingrid Weir A Not So Typical "Anniversary" Blog Post:Six years ago this week, I …

The 2019 World Parkinson Congress in Kyoto, Japan

"Learning is not attained by chance, it must be sought for with ardor and diligence." Abigail Adams "Believe in yourself and all that you are. Know that there is something inside you that is greater than any obstacle." Christian D. Larson Introduction to the 5th World Parkinson Congress (WPC) in Kyoto, Japan from June 4-7, …

Hope- 2019 Parkinson’s Awareness Month

"Hope is passion for what is possible." Soren Kierkegaard "What oxygen is to the lungs, such is hope to the meaning of life." Emil Brunner 2019 Parkinson's Awareness Month: To help support the month of Parkinson's awareness, here are 3-posts from earlier in April-•2019 Parkinson’s Awareness Month- 12 Rules of Life With Exercise•2019 Parkinson’s Awareness Month …

2019 Parkinson’s Awareness Month- 12 Rules of Life With Exercise

"If we could give every individual the right amount of nourishment and exercise, not too little and not too much, we would have found the safest way to health." Hippocrates "Patients should have rest, food, fresh air, and exercise - the quadrangle of health." William Osler Introduction: April is Parkinson's Awareness Month. I am convinced …

Neurological Mayhem by Dual Antioxidative and Anti-inflammatory Agents in Aged Parkinson’s Mice

"No person was ever honored for what he received. Honor has been the reward for what he gave." Calvin Coolidge "The most reliable way to predict the future is to create it." Abraham Lincoln Introduction: Recently, Jeff Keegan asked me if I had seen the paper by Gil-Martínez et al., an established Parkinson's research group …

Parkinson’s and Sialorrhea (Drooling or Excessive Salivation)

"The good physician treats the disease; the great physician treats the patient who has the disease." Sir William Osler "Listen to your patient, he is telling you the diagnosis." Sir William Osler Précis: The medical term used for excessive drooling is sialorrhea [si·al·or·rhe·a (sī-ăl′ə-rē′ə)]. Hockstein et al. said, "Sialorrhea (drooling or excessive salivation) is a …

Whey Protein Supplements May Increase Glutathione in Parkinson’s

"Basic research is what I am doing when I don't know what I am doing." Wernher von Braun "As far as the laws of mathematics refer to reality, they are not certain, and as far as they are certain, they do not refer to reality." Albert Einstein Overview: In 1989, Riederer and others demonstrated that …