Parkinson’s: Don’t Stop

"When you can stop you don't want to, and when you want to stop, you can't." Luke Davies "The question isn't who is going to let me; it's who is going to stop me." Ayn Rand Don't Stop:Attitude determines much in our lives.Looking positively to the future can bolster your goals.Perspective especially matters for someone …

Fatigue in Parkinson’s

"Fatigue is the best pillow." Benjamin Franklin "Fatigue roughens up the edges of your nerves; it exposes your fears and your weaknesses." June Havoc Introduction: Fatigue is a standard part of everyday life. Fatigue is especially prevalent in the Parkinson's community. Herein is a brief overview of fatigue in people (person)-with-Parkinson's (PwP). "Many fears are born …

Word for Wednesday: Parkinsonism

"A correct diagnosis is three-fourths the remedy." Mahatma Gandhi "The art of clinical diagnosis lies in the ability to ask the right questions." Harriet B. Braiker What is Parkinsonism? How is this different from Parkinson's? Parkinson's is a neurodegenerative disorder that destroys dopamine-producing dopaminergic neurons. As Parkinson's progresses, other brain areas are affected, leading to motor- …

Happy New Year (2023) from the Journey with Parkinson’s

"Let us resolve to do the best we can with what we've got." William Feather "Maybe this year, we ought to walk through the rooms of our lives not looking for flaws, but looking for potential." Ellen Goodman Happy New Year! In the New Year, may you maintain excellent health, create quality time for loved …

A Graph of Your Daily Level of Exogenous Levodopa

"The greatest achievement is to outperform yourself." Denis Waitley "Sometimes, carrying on, just carrying on, is the superhuman achievement." Albert Camus Introduction: Have you been taking carbidopa/levodopa to treat your Parkinson's? Are you experiencing any off-on periods? Do you have any dyskinesia? Do you think it's time to change your dosing pattern or the timing …

Update on Palmitoylethanolamide (PEA) for the Treatment of Parkinson’s

"To the sick, while there is life there is hope. [Lat., Aegroto dum anima est, spes est.]" Marcus Tullius Cicero "We can’t live without hope. When we keep hoping, we keep living." Pete Wilson Introduction: Palmitoylethanolamide (PEA*) is a naturally occurring bioactive lipid that contains a fatty acid moiety and ethanolamide. The molecular formula of …

Effect of Posture and Motility on Drug Availability in the Human Stomach

"The good thing about science is that it's true whether or not you believe in it." Neil deGrasse Tyson "Imagination is more important than knowledge." Albert Einstein Introduction:  Taking something by mouth is a common and relatively easy way to administer a drug. By contrast, when you carefully consider the route, it is a more complex …

The Aging Immune System and Parkinson’s

"Come grow old with me. The best is yet to be." William Wordsworth "As long as I am breathing, in my eyes, I am just beginning." Criss Jami Introduction: Recently, an exciting and in-depth review article about inflammation and the immune system and their dysfunction in the pathway of Parkinson's was published. The citation for …

Science Sunday: Cinnamon’s Neuroprotective Potential in Parkinson’s

"The doctor of the future will no longer treat the human frame with drugs, but rather will cure and prevent disease with nutrition." Thomas A. Edison "Our food should be our medicine and our medicine should be our food." Hippocrates Introduction: Besides being used in foods as a spice, cinnamon has been used for many …

Role of Palmitoylethanolamide to Control Neuroinflammation and Potential Therapy for Parkinson’s

"Our destiny is not determined by the number of times we stumble but by the number of times we rise up, dust ourselves off, and move forward." Dieter F. Uchtdorf "My motto was always to keep swinging. Whether I was in a slump or feeling bad or having trouble off the field, the only thing …

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