"I am really very, very tired of everything - more than tired." Friedrich Nietzsche "There are wounds that never show on the body that are deeper and more hurtful than anything that bleeds." Laurell K. Hamilton Anhedonia and Parkinson's: Anhedonia is a non-motor-related problem in Parkinson's. It is a core symptom of depression in Parkinson's …
9 Ways to Give Yourself a Break During Your Journey With Parkinson’s
"We have to learn to be our own best friends because we fall too easily into the trap of being our own worst enemies." Roderick Thorp "Your playing small doesn't serve the world." Marianne Williamson What does it mean to give yourself a break? A commitment to doing something kind for yourself. It matters not …
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Ten Summary Points From Mitchell AK, Bliss RR, Church FC. Exercise, Neuroprotective Exerkines, and Parkinson’s Disease: A Narrative Review. Biomolecules. 2024;14(10).
"To enjoy the glow of good health, you must exercise." Gene Tunney "Lack of activity destroys the good condition of every human being" Plato Introduction: When we were growing up, we had shortcuts to reading the big classic books; we had "Cliff Notes." Our teachers hated them because it was one person expressing their opinion. Personally, …
Parkinson’s: The Eyes Have It
"It never hurts your eyesight to look on the bright side of things." Barbara Johnson "Vision is seeing visibly the light of hope within the range of the eyesight." Anuj Introduction: There is no doubt that with age comes a worsening of vision. Furthermore, there is also an effect on one's eyesight by Parkinson's. Consider …
2023 Parkinson’s Awareness Month and 120 Quotes to Support Your Journey
"He who has health, has hope; and he who has hope, has everything." Thomas Carlyle "Health is like money, we never have a true idea of its value until we lose it." Josh Billings Introduction: For whatever reason, quotes have been a part of most of my blog posts. It is not like I have …
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A Graph of Your Daily Level of Exogenous Levodopa
"The greatest achievement is to outperform yourself." Denis Waitley "Sometimes, carrying on, just carrying on, is the superhuman achievement." Albert Camus Introduction: Have you been taking carbidopa/levodopa to treat your Parkinson's? Are you experiencing any off-on periods? Do you have any dyskinesia? Do you think it's time to change your dosing pattern or the timing …
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Effect of Posture and Motility on Drug Availability in the Human Stomach
"The good thing about science is that it's true whether or not you believe in it." Neil deGrasse Tyson "Imagination is more important than knowledge." Albert Einstein Introduction: Taking something by mouth is a common and relatively easy way to administer a drug. By contrast, when you carefully consider the route, it is a more complex …
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Science Sunday: Cinnamon’s Neuroprotective Potential in Parkinson’s
"The doctor of the future will no longer treat the human frame with drugs, but rather will cure and prevent disease with nutrition." Thomas A. Edison "Our food should be our medicine and our medicine should be our food." Hippocrates Introduction: Besides being used in foods as a spice, cinnamon has been used for many …
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Importance of Magnesium in the Brain and Magnesium Threonate is Neuroprotective in a Mouse Model of Parkinson’s
"The world may be broken, but hope is not crazy." John Green "Our eternal message of hope is that dawn will come." Martin Luther King, Jr. Introduction: Epidemiological studies show that magnesium deficiency is associated with a Parkinson's like syndrome called Parkinson-Dementia Syndrome (PDC). PDC patients have progressive cognitive decline, parkinsonian, and the loss of the …
Human Gut Microbes Identified That Process Levodopa
"Symbiosis is a much higher reflection of intelligent life." Frederick Lenz "Why do we do basic research? To learn about ourselves." Walter Gilbert Overview: Reading the article entitled "Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism" from V. Maini Rekdal et al., Science 364, eaau6323 (2019) (DOI: 10.1126/science.aau6323- open access) made …
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