Neurological Mayhem by Dual Antioxidative and Anti-inflammatory Agents in Aged Parkinson’s Mice

"No person was ever honored for what he received. Honor has been the reward for what he gave." Calvin Coolidge "The most reliable way to predict the future is to create it." Abraham Lincoln Introduction: Recently, Jeff Keegan asked me if I had seen the paper by Gil-Martínez et al., an established Parkinson's research group... Continue Reading →

Journey with Parkinson’s: Brief Reports on Current Research/Issues

"There is a single light of science, and to brighten it anywhere is to brighten it everywhere." Isaac Asimov “Live neither in the past nor in the future, but let each day’s work absorb your entire energies, and satisfy your widest ambition.”  Sir William Osler Introduction: For the following reasons, I would like to introduce and... Continue Reading →

Parkinson’s Awareness Month: The Science Behind How Exercise Slows Disease Progression

"Do not let what you cannot do interfere with what you can do." John Wooden "To enjoy the glow of good health, you must exercise." Gene Tunney Précis: For Parkinson's Awareness Month, let's begin with an important reminder/statement that "Exercise is medicine for Parkinson's disease."  Coming soon in a future blog post I will review... Continue Reading →

Neuroprotection with Taurine in a Parkinson’s Model System

"There is no medicine like hope, no incentive so great, and no tonic so powerful as expectation of something tomorrow." Orison Swett Marden "Hope sees the invisible, feels the intangible, and achieves the impossible." Helen Keller Introduction: Many of us take levodopa/carbidopa for substantial symptomatic relief; however, this dopamine replacement treatment only relieves symptoms without... Continue Reading →

The Yack on NAC (N-Acetyl-Cysteine) and Parkinson’s

"Once you choose hope, anything's possible." Christopher Reeve "Hope is like a road in the country; there was never a road, but when many people walk on it, the road comes into existence." Lin Yutang Introduction: N-Acetyl-Cysteine (or N-acetylcysteine, usually abbreviated NAC and frequently pronounced like the word 'knack') is an altered (modified by an... Continue Reading →

Importance of Model Systems in Parkinson’s Research

“Science is organized knowledge. Wisdom is organized life.” Will Duran “The most exciting phrase to hear in science, the one that heralds new discoveries, is not 'Eureka!' but 'That's funny...'” Isaac Asimov Introduction:  The goal of this post is to highlight several experimental model systems that have effectively been used in Parkinson's research.  We  have... Continue Reading →

Neuroprotection by Modified-Macrophages in a Parkinson’s Model System

“Somewhere, something incredible is waiting to be known.” Carl Sagan “You never change things by fighting the existing reality.  To change something, build a new model that makes the existing model obsolete.” R. Buckminster Fuller Précis: Scientists at the University of North Carolina at Chapel Hill are using an innovative approach to treat Parkinson's in... Continue Reading →

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