Déjà Vu and Neuroplasticity in Parkinson’s

“Continuous effort - not strength or intelligence - is the key to unlocking our potential.” Winston S. Churchill “...remember that what has once been done may be done again.” Alexandre Dumas Introducing the terms: Déjà vu: "A feeling of having already experienced the present situation." (http://www.oxforddictionaries.com/us/definition/american_english/) Neuroplasticity: "The brain's ability to reorganize itself by forming …

Parkinson’s and the Positivity of Michael J. Fox

“For everything this disease has taken, something with greater value has been given–sometimes just a marker that points me in a new direction that I might not otherwise have traveled. So, sure, it may be one step forward and two steps back, but after a time with Parkinson’s, I’ve learned that what is important is …

Importance of Model Systems in Parkinson’s Research

“Science is organized knowledge. Wisdom is organized life.” Will Duran “The most exciting phrase to hear in science, the one that heralds new discoveries, is not 'Eureka!' but 'That's funny...'” Isaac Asimov Introduction:  The goal of this post is to highlight several experimental model systems that have effectively been used in Parkinson's research.  We  have …

Hope in the Presence of Parkinson’s

“Never lose faith in yourself, and never lose hope; remember, even when this world throws its worst and then turns its back, there is still always hope.” Pittacus Lore "Hope is a function of struggle.” Brené Brown Beginning of the story: Tuesday, I drove from Chapel Hill, North Carolina to Blacksburg, Virginia (~3 1/2 hours, …

11 Tips And Character Traits For Living Better With Parkinson’s

"In the New Year, may your right hand always be stretched out in friendship but never in want." Irish Toast “As long as I am breathing, in my eyes, I am just beginning.” Criss Jami Happy New Year! Thanks for all of your support, feedback, responses and suggestions in 2015; they were most appreciated. 2016 …

The Song of the Journey Ahead is About Living Authentically in the Presence of Parkinson’s

“Choosing one path means abandoning others – if you try to follow every possible path you will end up following none.” Paulo Coelho "An awareness of one's mortality can lead you to wake up and live an authentic, meaningful life." Bernie Siegel A beginning: ~7 people/hour are diagnosed with Parkinson's in the USA; resulting in …

Anti-malaria Drugs Target Nurr1 For Possible Parkinson’s Therapeutics

“When prescribing one of the drugs I take, my doctor warned me of a common side effect: exaggerated, intensely vivid dreams. To be honest, I've never really noticed the difference. I've always dreamt big.” Michael J. Fox Parkinson's description: About 60,000 new Parkinson's cases will be diagnosed this year in the USA; joining the 1 …

Personal Strengths of Character

"Perhaps I am stronger than I think." Thomas Merton “Do not pray for an easy life, pray for the strength to endure a difficult one.”  Bruce Lee See yourself with strength: Life comes with varying conditions, such as easy/hard, simple/complicated, happy/sad, successful/unsuccessful, short/long and healthy/sick.  Being prepared is always good; especially if the equation becomes …

Leucine-rich Repeat Kinase 2 (LRRK2) Is A Possible Target For Therapy In Parkinson’s

“Research is the process of going up alleys to see if they are blind.”  Marston Bates “What we find changes who we become.”  Peter Morville The reality of Parkinson's: Parkinson’s is a common neurodegenerative disorder. Approximately 60,000 new cases/year of Parkinson's occur in the USA, and they join ~1 million people living here with this …

Believe In Big Movements Of LSVT BIG Physical Therapy For Parkinson’s

“Notice that the stiffest tree is most easily cracked, while the bamboo or willow survives by bending with the wind.” Bruce Lee "Only those who will risk going too far can possibly find out how far one can go." T.S. Eliot Believe:  I believe that staying positive will help control the course of my Parkinson's.  …