Basal Ganglia, Nigrostriatal Pathway and Parkinson’s

"Hope arouses, as nothing else can arouse, a passion for the possible." William Sloane Coffin "Walk on, walk on with hope in your heart, and you'll never walk alone, you'll never walk alone." Oscar Hammerstein II Introduction: I have been trying to learn more about brain physiology and the inner workings as it relates to …

Cytokines Linked to Motor and Non-Motor Symptoms of Parkinson’s

"Do the difficult things while they are easy and do the great things while they are small. A journey of a thousand miles must begin with a single step." Lao Tzu "When I let go of what I am, I become what I might be." Lao Tzu Introduction: There are many ways that Parkinson’s begins. …

Life With Parkinson’s

"Hope makes a good breakfast. Eat plenty of it." Ian Fleming "Learn from yesterday, live for today." Albert Einstein Introduction: In early March, 2015, I began this blog. And I closed the first blog post as follows: "In closing this opening blog, I am trying to live life well and authentically, and not be defined …

Parkinson’s: Reflective Gratitude of Life

"We don't need more to be thankful for, we just need to be more thankful." Carlos Castaneda "Take as a gift whatever the day brings forth." Horace Introduction: The title of this blog post says it all. At the age of 66 years old, I stand before you thinking I need to be more thankful. Really? …

Go FAR and Be ADEPT With Exercises For Parkinson’s

"You can't get much done in life if you only work on the days when you feel good." Jerry West "Always make a total effort, even when the odds are against you." Arnold Palmer Précis: By now, everyone knows the importance of exercise. However, in my opinion, you cannot hear it enough. Exercise is Medicine, especially …

Living Well With Parkinson’s

"Live well, learn plenty, laugh often, love much." Ralph Waldo Emerson "He who has a why to live can bear almost any how." Friedrich Nietzsche **Introduction: Recently, I wrote a blog post entitled "A Checklist for Supporting Someone with Parkinson’s" (to read it click here). Briefly, I had been meeting people who had friends with …

The 2019 World Parkinson Congress in Kyoto, Japan

"Learning is not attained by chance, it must be sought for with ardor and diligence." Abigail Adams "Believe in yourself and all that you are. Know that there is something inside you that is greater than any obstacle." Christian D. Larson Introduction to the 5th World Parkinson Congress (WPC) in Kyoto, Japan from June 4-7, …

The Practical Matter of Carrying Medication for Treating Parkinson’s

"Trust yourself. Create the kind of self that you will be happy to live with all your life." Golda Meir "Start where you are, use what you have." Arthur Ashe Introduction: Within 24 hours of arriving in Kyoto, Japan for the World Parkinson Congress (June 2019), I was asked by several people, "How did I …

The Uncertainty of Parkinson’s

"In these matters the only certainty is that nothing is certain." Pliny the Elder "Knowledge is an unending adventure at the edge of uncertainty." Jacob Bronowski Précis: There are many motor and non-symptoms in Parkinson's, which gives us our own individual expression pattern of this chronic neurodegenerative disease. A common thread we share is linked …

Human Gut Microbes Identified That Process Levodopa

"Symbiosis is a much higher reflection of intelligent life." Frederick Lenz "Why do we do basic research? To learn about ourselves." Walter Gilbert Overview: Reading the article entitled "Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism" from V. Maini Rekdal et al., Science 364, eaau6323 (2019) (DOI: 10.1126/science.aau6323- open access) made …