Parkinson’s and the Positivity of Michael J. Fox

“For everything this disease has taken, something with greater value has been given–sometimes just a marker that points me in a new direction that I might not otherwise have traveled. So, sure, it may be one step forward and two steps back, but after a time with Parkinson’s, I’ve learned that what is important is …

Importance of Model Systems in Parkinson’s Research

“Science is organized knowledge. Wisdom is organized life.” Will Duran “The most exciting phrase to hear in science, the one that heralds new discoveries, is not 'Eureka!' but 'That's funny...'” Isaac Asimov Introduction:  The goal of this post is to highlight several experimental model systems that have effectively been used in Parkinson's research.  We  have …

Hope in the Presence of Parkinson’s

“Never lose faith in yourself, and never lose hope; remember, even when this world throws its worst and then turns its back, there is still always hope.” Pittacus Lore "Hope is a function of struggle.” Brené Brown Beginning of the story: Tuesday, I drove from Chapel Hill, North Carolina to Blacksburg, Virginia (~3 1/2 hours, …

Neuroprotection by Modified-Macrophages in a Parkinson’s Model System

“Somewhere, something incredible is waiting to be known.” Carl Sagan “You never change things by fighting the existing reality.  To change something, build a new model that makes the existing model obsolete.” R. Buckminster Fuller Précis: Scientists at the University of North Carolina at Chapel Hill are using an innovative approach to treat Parkinson's in …

11 Tips And Character Traits For Living Better With Parkinson’s

"In the New Year, may your right hand always be stretched out in friendship but never in want." Irish Toast “As long as I am breathing, in my eyes, I am just beginning.” Criss Jami Happy New Year! Thanks for all of your support, feedback, responses and suggestions in 2015; they were most appreciated. 2016 …

Potential New Parkinson’s Drug Highlight: the Leukemia Drug Nilotinib

“With Parkinson’s you have two choices: You can let it control you, or you can control it. And I’ve chosen to control it.” US Senator Isakson “Learn from yesterday, live for today, hope for tomorrow. The important thing is to not stop questioning.” Albert Einstein Introduction: In my academic career to-date, my research group and I …

6 Personal Strengths for Living Decisively with Parkinson’s

“How are they going to see me — as the colleague as I have always been, or as the patient I always will be? That was the beginning of my transition.” Alice Lazzarini (a Parkinson’s researcher who was diagnosed with Parkinson's) Précis: After successfully hitting a golf ball out of a sand trap and onto …

Moving Day® was a Morning to Move for Parkinson’s and a Time to be Moved

“We either make ourselves miserable or we make ourselves strong. The amount of work is the same.”  Carlos Castenada “Don’t be ashamed of your story, it will inspire others.” Unknown Background story: Over the years, my research career has been supported by various non-Federal organizations, in particular the American Heart Association (AHA) and Susan G. …

Science of Advanced Age as a Risk Factor for Parkinson’s

“Spring passes and one remembers one's innocence. Summer passes and one remembers one's exuberance. Autumn passes and one remembers one's reverence. Winter passes and one remembers one's perseverance.” Yoko Ono “Embrace aging.” Mitch Albom, Tuesdays with Morrie Précis: The great majority of individuals with Parkinson's reveal no genetic mutations, no past history of head injury, …

Gender Differences as a Factor in Parkinson’s

"Men are from Earth, women are from Earth. Deal with it.” George Carlin “You can either be a victim of the world or an adventurer in search of treasure. It all depends on how you view your life.” Paulo Coelho Précis: ~10% of Parkinson's cases are linked to familial genetic mutations; whereas the vast majority …