The Yack on NAC (N-Acetyl-Cysteine) and Parkinson’s

"Once you choose hope, anything's possible." Christopher Reeve "Hope is like a road in the country; there was never a road, but when many people walk on it, the road comes into existence." Lin Yutang Introduction: N-Acetyl-Cysteine (or N-acetylcysteine, usually abbreviated NAC and frequently pronounced like the word 'knack') is an altered (modified by an …

Parkinson’s Disease Research: A Commentary from the Stands and the Playing Field

"You can have a very bad end with Parkinson's, but on the other hand, you can be like me, because I'm lucky. I'm not having a bad end." Margo MacDonald "My age makes me think how valuable life is. How bad is something like Parkinson's in relation to not having life at all?" Michael J. …

Milestones in Parkinson’s Disease Research and Discovery

"The real voyage of discovery consists not in seeking new landscapes, but in having new eyes." Marcel Proust "The process of scientific discovery is, in effect, a continual flight from wonder." Albert Einstein Preface:  Happy birthday to James Parkinson (neurologist, geologist, scientist, activist),  born April 11, 1755 and died December 21, 1824.  World Parkinson's Day …

“Go the Distance” With MAO-B Inhibitors: Potential Long-term Benefits in Parkinson’s

"Life is 10 percent what you make it, and 90 percent how you take it." Irving Berlin "My attitude is that if you push me towards something that you think is a weakness, then I will turn that perceived weakness into a strength." Michael Jordan Précis:  (1) A brief review of the major classes of …

Part 2: Journey to Parkinson’s and Magnetic Resonance Imaging

"The best thing about the future is that it comes one day at a time." Abraham Lincoln "To be yourself in a world that is constantly trying to make you something else is the greatest accomplishment." Ralph Waldo Emerson Along the way to the diagnosis of Parkinson’s, you may have to undergo several different kinds …

2016: The Year in Parkinson’s

“The most beautiful experience we can have is the mysterious. It is the fundamental emotion that stands at the cradle of true art and true science.” Albert Einstein “Your assumptions are your windows on the world. Scrub them off every once in a while, or the light won't come in.” Isaac Asimov Summary: (Part 1) …

Catching Up, Life-Stories, and Future Posts in Journey With Parkinson’s

"One isn't necessarily born with courage, but one is born with potential. Without courage, we cannot practice any other virtue with consistency. We can't be kind, true, merciful, generous, or honest." Maya Angelou "Life is not a problem to be solved, but an experience to be had." Alan Watts Don't You Get The Summer Off?: …

Part 1: Journey to Parkinson’s and Barium Swallow

“It does not do to dwell on dreams and forget to live.” J.K. Rowling, Harry Potter and the Sorcerer's Stone “May you live every day of your life.” Jonathan Swift  Introduction: Along the way to the diagnosis of Parkinson’s, you may have to undergo several different kinds of examinations. These tests will help your physician(s) …

Parkinson’s Treatment With Dopamine Agonist, Complementary and Alternative Medicine (CAM), and Exercise

“Stop taking identity in illness and start taking identity in wellness” Nina Leavins “The thought of hope is the seed to healing.” Shilpa Menon Précis: Several of you have asked for an update on my strategy for treating my  Parkinson's.  My current plan consists of traditional Parkinson's medication,  augmented by a complementary and alternative medicine …

Importance of Model Systems in Parkinson’s Research

“Science is organized knowledge. Wisdom is organized life.” Will Duran “The most exciting phrase to hear in science, the one that heralds new discoveries, is not 'Eureka!' but 'That's funny...'” Isaac Asimov Introduction:  The goal of this post is to highlight several experimental model systems that have effectively been used in Parkinson's research.  We  have …