Neurological Mayhem by Dual Antioxidative and Anti-inflammatory Agents in Aged Parkinson’s Mice

"No person was ever honored for what he received. Honor has been the reward for what he gave." Calvin Coolidge "The most reliable way to predict the future is to create it." Abraham Lincoln Introduction: Recently, Jeff Keegan asked me if I had seen the paper by Gil-Martínez et al., an established Parkinson's research group …

Journey with Parkinson’s: Brief Reports on Current Research/Issues

"There is a single light of science, and to brighten it anywhere is to brighten it everywhere." Isaac Asimov “Live neither in the past nor in the future, but let each day’s work absorb your entire energies, and satisfy your widest ambition.”  Sir William Osler Introduction: For the following reasons, I would like to introduce and …

Diet and Dementia (Cognitive Decline) in the Aging

"When diet is wrong medicine is of no use. When diet is correct medicine is of no need.’’ Ancient Ayurvedic Proverb ‘‘What is food to one man may be fierce poison to others.’’ Lucretius (99 B.C.-55 BC). Précis: Last month in London, England, at the Alzheimer's Association International Conference (AAIC) 2017, there were several presentations …

Parkinson’s Disease Research: A Commentary from the Stands and the Playing Field

"You can have a very bad end with Parkinson's, but on the other hand, you can be like me, because I'm lucky. I'm not having a bad end." Margo MacDonald "My age makes me think how valuable life is. How bad is something like Parkinson's in relation to not having life at all?" Michael J. …

The Evolving Portrait of Parkinson’s

“Aging is not lost youth but a new stage of opportunity and strength.” Betty Friedane  “If we own the story then we can write the ending.” Brené Brown Précis:  To showcase the amazing art/photography/videography of Anders M. Leines who lives in Norway, which gives me the opportunity to voice an opinion about the emerging picture/image …

Déjà Vu and Neuroplasticity in Parkinson’s

“Continuous effort - not strength or intelligence - is the key to unlocking our potential.” Winston S. Churchill “...remember that what has once been done may be done again.” Alexandre Dumas Introducing the terms: Déjà vu: "A feeling of having already experienced the present situation." (http://www.oxforddictionaries.com/us/definition/american_english/) Neuroplasticity: "The brain's ability to reorganize itself by forming …

Importance of Model Systems in Parkinson’s Research

“Science is organized knowledge. Wisdom is organized life.” Will Duran “The most exciting phrase to hear in science, the one that heralds new discoveries, is not 'Eureka!' but 'That's funny...'” Isaac Asimov Introduction:  The goal of this post is to highlight several experimental model systems that have effectively been used in Parkinson's research.  We  have …