The 23andMe Parkinson’s Research Study

"Somewhere, something incredible is waiting to be known." Carl Sagan "A dream doesn't become reality through magic; it takes sweat, determination and hard work." Colin Powell Introduction/Background: Parkinson’s disease is a neurodegenerative disorder that affects movement. It evolves slowly, usually starting as either stiffness in a hand or a small tremor. Over time, Parkinson’s progresses; …

The Evolving Portrait of Parkinson’s

“Aging is not lost youth but a new stage of opportunity and strength.” Betty Friedane  “If we own the story then we can write the ending.” Brené Brown Précis:  To showcase the amazing art/photography/videography of Anders M. Leines who lives in Norway, which gives me the opportunity to voice an opinion about the emerging picture/image …

Catching Up, Life-Stories, and Future Posts in Journey With Parkinson’s

"One isn't necessarily born with courage, but one is born with potential. Without courage, we cannot practice any other virtue with consistency. We can't be kind, true, merciful, generous, or honest." Maya Angelou "Life is not a problem to be solved, but an experience to be had." Alan Watts Don't You Get The Summer Off?: …

Part 1: Journey to Parkinson’s and Barium Swallow

“It does not do to dwell on dreams and forget to live.” J.K. Rowling, Harry Potter and the Sorcerer's Stone “May you live every day of your life.” Jonathan Swift  Introduction: Along the way to the diagnosis of Parkinson’s, you may have to undergo several different kinds of examinations. These tests will help your physician(s) …

Parkinson’s Treatment With Dopamine Agonist, Complementary and Alternative Medicine (CAM), and Exercise

“Stop taking identity in illness and start taking identity in wellness” Nina Leavins “The thought of hope is the seed to healing.” Shilpa Menon Précis: Several of you have asked for an update on my strategy for treating my  Parkinson's.  My current plan consists of traditional Parkinson's medication,  augmented by a complementary and alternative medicine …

Importance of Model Systems in Parkinson’s Research

“Science is organized knowledge. Wisdom is organized life.” Will Duran “The most exciting phrase to hear in science, the one that heralds new discoveries, is not 'Eureka!' but 'That's funny...'” Isaac Asimov Introduction:  The goal of this post is to highlight several experimental model systems that have effectively been used in Parkinson's research.  We  have …

Potential New Parkinson’s Drug Highlight: the Leukemia Drug Nilotinib

“With Parkinson’s you have two choices: You can let it control you, or you can control it. And I’ve chosen to control it.” US Senator Isakson “Learn from yesterday, live for today, hope for tomorrow. The important thing is to not stop questioning.” Albert Einstein Introduction: In my academic career to-date, my research group and I …

Sleep, Relaxation, And Traveling

"It's very important that we re-learn the art of resting and relaxing. Not only does it help prevent the onset of many illnesses that develop through chronic tension and worrying; it allows us to clear our minds, focus, and find creative solutions to problems."  Thich Nhat Hanh Part 1, Sleep and Parkinson's: Although it's a …

Leucine-rich Repeat Kinase 2 (LRRK2) Is A Possible Target For Therapy In Parkinson’s

“Research is the process of going up alleys to see if they are blind.”  Marston Bates “What we find changes who we become.”  Peter Morville The reality of Parkinson's: Parkinson’s is a common neurodegenerative disorder. Approximately 60,000 new cases/year of Parkinson's occur in the USA, and they join ~1 million people living here with this …

Believe In Big Movements Of LSVT BIG Physical Therapy For Parkinson’s

“Notice that the stiffest tree is most easily cracked, while the bamboo or willow survives by bending with the wind.” Bruce Lee "Only those who will risk going too far can possibly find out how far one can go." T.S. Eliot Believe:  I believe that staying positive will help control the course of my Parkinson's.  …