Purple Haze of Parkinson’s: How Dopamine Works

"Life has many ways of testing a person's will, either by having nothing happen at all or by having everything happen all at once.”  Paulo Coelho Précis: To briefly describe the biochemistry of dopamine and dopamine receptors, dopamine physiology, and therapeutic strategies for replacing dopamine in Parkinson's.  But first, some "Purple Haze" by the Jimi …

The Generosity of Donating Your Body to Medical Science

“Don't cry because it's over, smile because it happened.”  Dr. Seuss “May you live every day of your life.”  Jonathan Swift Pros and cons to donating your body to medical science: Likely you've heard about it, maybe you've even thought about it, donating your body to medical science?  It is a generous and altruistic decision …

Anti-malaria Drugs Target Nurr1 For Possible Parkinson’s Therapeutics

“When prescribing one of the drugs I take, my doctor warned me of a common side effect: exaggerated, intensely vivid dreams. To be honest, I've never really noticed the difference. I've always dreamt big.” Michael J. Fox Parkinson's description: About 60,000 new Parkinson's cases will be diagnosed this year in the USA; joining the 1 …

Leucine-rich Repeat Kinase 2 (LRRK2) Is A Possible Target For Therapy In Parkinson’s

“Research is the process of going up alleys to see if they are blind.”  Marston Bates “What we find changes who we become.”  Peter Morville The reality of Parkinson's: Parkinson’s is a common neurodegenerative disorder. Approximately 60,000 new cases/year of Parkinson's occur in the USA, and they join ~1 million people living here with this …