Manganese-induced Parkinsonism Compared to Parkinson’s Disease

"Science is a way of thinking much more than it is a body of knowledge." Carl Sagan "Imagination is more important than knowledge." Albert Einstein What is Manganese? Manganese is abbreviated by the symbol Mn and it is atomic number 25 (see Periodic Table of the Elements).  Manganese is considered a transition metal, which is …

Neurological Mayhem by Dual Antioxidative and Anti-inflammatory Agents in Aged Parkinson’s Mice

"No person was ever honored for what he received. Honor has been the reward for what he gave." Calvin Coolidge "The most reliable way to predict the future is to create it." Abraham Lincoln Introduction: Recently, Jeff Keegan asked me if I had seen the paper by Gil-Martínez et al., an established Parkinson's research group …

Brief Report: Benefit of Probiotic Supplements in Parkinson’s

“Taking probiotics is a habit that can really benefit the digestive system, which is intricately connected to our overall health.”  Dr. Michael F. Roizen “Compelling new studies are showing how probiotics can help keep healthy people healthy. One study showed a decreased incidence of common infectious diseases among kids in day care.”  Dr. Mary Ellen …

Journey with Parkinson’s: Brief Reports on Current Research/Issues

"There is a single light of science, and to brighten it anywhere is to brighten it everywhere." Isaac Asimov “Live neither in the past nor in the future, but let each day’s work absorb your entire energies, and satisfy your widest ambition.”  Sir William Osler Introduction: For the following reasons, I would like to introduce and …

Dopamine Agonists and Impulse Control Disorders in Parkinson’s

"Whenever you are immersed in compulsive thinking, you are avoiding what is. You don't want to be where you are. Here, Now." Eckhart Tolle "Somewhere between obsession and compulsion is impulse." Alexander Pushkin Introduction: In the latest issue of Neurology (June, 2018), Dr. Corvol and collaborators in Paris, France, present the results of a long-term …

Neuroprotection with Taurine in a Parkinson’s Model System

"There is no medicine like hope, no incentive so great, and no tonic so powerful as expectation of something tomorrow." Orison Swett Marden "Hope sees the invisible, feels the intangible, and achieves the impossible." Helen Keller Introduction: Many of us take levodopa/carbidopa for substantial symptomatic relief; however, this dopamine replacement treatment only relieves symptoms without …

Dopamine Agonist Withdrawal Syndrome (DAWS) in Parkinson’s

"Some remedies are worse than the disease." Publilius Syrus "Each patient carries his own doctor inside him." Norman Cousins Summary: Dopamine agonists are widely used in the treatment of Parkinson's, especially as a first-line therapy. Some patients on a dopamine agonist experience side-effects that require either tapering or discontinuation of the drug.  First described in …