"The excitement of vitamins, nutrition and metabolism permeated the environment." Paul D. Boyer "A substance that makes you ill if you don't eat it." Albert Szent-Gyorgy Introduction: Claire McLean, an amazing-PT who is vital to my life managing my Parkinson's, posted a very interesting article about the generation of homocysteine from the metabolism of levodopa …
Milestones in Parkinson’s Disease Research and Discovery
"The real voyage of discovery consists not in seeking new landscapes, but in having new eyes." Marcel Proust "The process of scientific discovery is, in effect, a continual flight from wonder." Albert Einstein Preface: Happy birthday to James Parkinson (neurologist, geologist, scientist, activist), born April 11, 1755 and died December 21, 1824. World Parkinson's Day …
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“Go the Distance” With MAO-B Inhibitors: Potential Long-term Benefits in Parkinson’s
"Life is 10 percent what you make it, and 90 percent how you take it." Irving Berlin "My attitude is that if you push me towards something that you think is a weakness, then I will turn that perceived weakness into a strength." Michael Jordan Précis: (1) A brief review of the major classes of …
200 Years Ago James Parkinson published “An Essay On The Shaking Palsy”
"I have a form of Parkinson's disease, which I don't like. My legs don't move when my brain tells them to. It's very frustrating." George H.W. Bush "I discovered that I was part of a Parkinson's community with similar experiences and similar questions that I'd been dealing with alone." Michael J. Fox Summary: Two hundred …
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2016: The Year in Parkinson’s
“The most beautiful experience we can have is the mysterious. It is the fundamental emotion that stands at the cradle of true art and true science.” Albert Einstein “Your assumptions are your windows on the world. Scrub them off every once in a while, or the light won't come in.” Isaac Asimov Summary: (Part 1) …
The Mask of Parkinson’s
"I wear the mask. It does not wear me." Man in the Iron Mask "See to it, then, that the light within you is not darkness." Luke 11:35 Précis: The simplest way to describe Parkinson's is that it's a movement disorder due to the reduction of dopamine production. Sometimes one of the more obvious places …
Catching Up, Life-Stories, and Future Posts in Journey With Parkinson’s
"One isn't necessarily born with courage, but one is born with potential. Without courage, we cannot practice any other virtue with consistency. We can't be kind, true, merciful, generous, or honest." Maya Angelou "Life is not a problem to be solved, but an experience to be had." Alan Watts Don't You Get The Summer Off?: …
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Treatment of Parkinson’s Psychosis with Nuplazid
“At what point do you give up - decide enough is enough? There is only one answer really. Never.” Tabitha Suzuma "Be proud of your scars. They remind you that you have the will to live." Paulo Coelho Précis: ~50% of the people with Parkinson's develop psychotic tendencies. Treatment of their psychosis can be relatively …
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Parkinson’s Treatment With Dopamine Agonist, Complementary and Alternative Medicine (CAM), and Exercise
“Stop taking identity in illness and start taking identity in wellness” Nina Leavins “The thought of hope is the seed to healing.” Shilpa Menon Précis: Several of you have asked for an update on my strategy for treating my Parkinson's. My current plan consists of traditional Parkinson's medication, augmented by a complementary and alternative medicine …
Importance of Model Systems in Parkinson’s Research
“Science is organized knowledge. Wisdom is organized life.” Will Duran “The most exciting phrase to hear in science, the one that heralds new discoveries, is not 'Eureka!' but 'That's funny...'” Isaac Asimov Introduction: The goal of this post is to highlight several experimental model systems that have effectively been used in Parkinson's research. We have …
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